Two views of the same idea. The forces shows the actual hydrogen bonds, salt bridges, and hydrophobic core inside a real, experimentally-determined structure. The funnel shows why those forces let a chain find its shape without an impossible blind search.
Contacts are computed live from the deposited coordinates with standard geometric cut-offs:
hydrogen bonds as backbone N···O closer than 3.5 Å (residues
≥2 apart), salt bridges as acidic O (Asp/Glu) to basic N (Lys/Arg/His) closer than
4.0 Å — the two participating side chains are drawn as sticks and labelled,
acidic (negative) in red and basic (positive) in blue, so you can see each bridge is a pair of
nearby oppositely-charged side chains — disulfides as S–S closer than 2.5 Å. Structures from the
PDB; viewer built with
3Dmol.js.